Study of Parathyroid Hormone and Vitamin D Levels in Women with Renal Failure

Abstract

Objective: Because chronic kidney disease (CKD) is widely linked to a number of comorbidities, elevated cardiovascular issues, mortality events, and high medical costs, it is a major global health concern.
Vitamin D regulates the balance of calcium and phosphate and has a number of other skeletal impacts on human systems, including the neurological, cardiovascular, immunological, cell differentiation and growth, and hormonal systems. As CKD worsens, the prevalence of 25-vitamin D insufficiency increases.

The aim of this study was to investigate the relationship between parathyroid hormone and Vit D levels and to study the variables resulting from their imbalance in patients with (CKD).

Methods: Participants who were between the ages of 30 and 65 and not pregnant were recruited after obtaining informed consent from 44 individuals who visited government clinics at Yarmouk Teaching Hospital. Assessments should be made of the complete blood count (CBC), lipid profiles, fasting sugar, liver and kidney biochemistry indicators, intact parathormone (PTH), and a total of 25 (OH) D-vitamin levels.

Results: Compared to controls, patients' blood calcium levels were noticeably lower. While blood PTH levels in patients are much higher than in controls when compared to controls, patients' blood Vit D levels are significantly lower and there was a notable rise in blood urea, creatinine, and PHO levels in patients compared to controls.