The role of hepatocyte growth factor/c-mesenchymal to epithelial transition (HGF/c-Met) signaling pathway In Hepatocellular Carcinoma (REVIEW)

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Published: Nov 10, 2024
DOI: https://doi.org/10.47059/ijmtlm/V27I4S/159
Keywords:
hepatocyte, critical, interactions, liver

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Mona A. Abu El-Makarem
Department of Internal Medicine, Faculty of Medicine, Minia University, Minia, Egypt.
Rania M. Bakri
Department of Clinical Pathology, South Egypt Cancer Institue, Assuit University, Assiut, Egypt.
Hatem A. Hassan
Department of Internal Medicine, Faculty of Medicine, Minia University, Minia, Egypt.
Mahmoud G. Ameen
Department of Pathology, South Egypt Cancer Institue, Assiut University, Assuit, Egypt.
Alshymaa A. Hassnine
Department of Tropical Medicine, Faculty of Medicine, Minia University, Minia, Egypt.
Islam S. Farahat
Department of Internal Medicine, Faculty of Medicine, Minia University, Minia, Egypt.
Nehal I. Abbas
Department of Clinical Pathology, Faculty of Medicine, Minia University, Egypt.

Abstract

Hepatocellular carcinoma (HCC) is a one of the most common causes of cancer-related deaths, with complex molecular pathogenesis and interactions. Among these, the hepatocyte growth factor (HGF) and its receptor c-Mesenchymal to epithelial transition (c-Met) have garnered attention for their critical roles in liver biology. Under physiological conditions, the HGF/c-Met signaling aids in tissue repair, regeneration, and homeostasis.

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How to Cite
Mona A. Abu El-Makarem, Rania M. Bakri, Hatem A. Hassan, Mahmoud G. Ameen, Alshymaa A. Hassnine, Islam S. Farahat, & Nehal I. Abbas. (2024). The role of hepatocyte growth factor/c-mesenchymal to epithelial transition (HGF/c-Met) signaling pathway In Hepatocellular Carcinoma (REVIEW). International Journal of Medical Toxicology and Legal Medicine, 27(4s), 1210–1218. https://doi.org/10.47059/ijmtlm/V27I4S/159
Issue
Vol. 27 No. 4s (2024): Sustainable Engineering Practices in Medical Laboratories
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